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Evaluating the potential of gold, silver, and silica nanoparticles to saturate mononuclear phagocytic system tissues under repeat dosing conditions

BACKGROUND: As nanoparticles (NPs) become more prevalent in the pharmaceutical industry, questions have arisen from both industry and regulatory stakeholders about the long term effects of these materials. This study was designed to evaluate whether gold (10 nm), silver (50 nm), or silica (10 nm) na...

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Detalles Bibliográficos
Autores principales: Weaver, James L., Tobin, Grainne A., Ingle, Taylor, Bancos, Simona, Stevens, David, Rouse, Rodney, Howard, Kristina E., Goodwin, David, Knapton, Alan, Li, Xiaohong, Shea, Katherine, Stewart, Sharron, Xu, Lin, Goering, Peter L., Zhang, Qin, Howard, Paul C., Collins, Jessie, Khan, Saeed, Sung, Kidon, Tyner, Katherine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5513057/
https://www.ncbi.nlm.nih.gov/pubmed/28716104
http://dx.doi.org/10.1186/s12989-017-0206-4