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3′ UTR G-quadruplexes regulate miRNA binding

MicroRNAs (miRNAs) are small noncoding RNAs that repress the translation of their target genes. It has previously been shown that a target's availability to miRNA can be affected by its structure. G-quadruplexes (G4) are noncanonical structures adopted by G-rich nucleic acids that have been sho...

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Detalles Bibliográficos
Autores principales: Rouleau, Samuel, Glouzon, Jean-Pierre Sehi, Brumwell, Andrea, Bisaillon, Martin, Perreault, Jean-Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5513062/
https://www.ncbi.nlm.nih.gov/pubmed/28473452
http://dx.doi.org/10.1261/rna.060962.117