P53-miR-191-SOX4 regulatory loop affects apoptosis in breast cancer

miRNAs have emerged as key participants of p53 signaling pathways because they regulate or are regulated by p53. Here, we provide the first study demonstrating direct regulation of an oncogenic miRNA, miR-191-5p, by p53 and existence of a regulatory feedback loop. Using a combination of qRT-PCR, pro...

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Detalles Bibliográficos
Autores principales: Sharma, Shivani, Nagpal, Neha, Ghosh, Prahlad C., Kulshreshtha, Ritu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5513068/
https://www.ncbi.nlm.nih.gov/pubmed/28450532
http://dx.doi.org/10.1261/rna.060657.117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5513068/
https://www.ncbi.nlm.nih.gov/pubmed/28450532
http://dx.doi.org/10.1261/rna.060657.117

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