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High-throughput and site-specific identification of 2′-O-methylation sites using ribose oxidation sequencing (RibOxi-seq)

Ribose methylation (2′-O-methylation, 2′-OMe) occurs at high frequencies in rRNAs and other small RNAs and is carried out using a shared mechanism across eukaryotes and archaea. As RNA modifications are important for ribosome maturation, and alterations in these modifications are associated with cel...

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Detalles Bibliográficos
Autores principales: Zhu, Yinzhou, Pirnie, Stephan P., Carmichael, Gordon G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5513074/
https://www.ncbi.nlm.nih.gov/pubmed/28495677
http://dx.doi.org/10.1261/rna.061549.117