Rho kinase proteins display aberrant upregulation in vascular tumors and contribute to vascular tumor growth

BACKGROUND: The serine/threonine protein kinases ROCK1 and 2 are key RhoA-mediated regulators of cell shape and cytoskeletal dynamics. These proteins perform multiple functions in vascular endothelial cell physiology and are attractive targets for cancer therapy based on their roles as oncogenes and...

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Detalles Bibliográficos
Autores principales: Amaya, Clarissa N., Mitchell, Dianne C., Bryan, Brad A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5513090/
https://www.ncbi.nlm.nih.gov/pubmed/28709411
http://dx.doi.org/10.1186/s12885-017-3470-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5513090/
https://www.ncbi.nlm.nih.gov/pubmed/28709411
http://dx.doi.org/10.1186/s12885-017-3470-7

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