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Loss of DIP2C in RKO cells stimulates changes in DNA methylation and epithelial-mesenchymal transition
BACKGROUND: The disco-interacting protein 2 homolog C (DIP2C) gene is an uncharacterized gene found mutated in a subset of breast and lung cancers. To understand the role of DIP2C in tumour development we studied the gene in human cancer cells. METHODS: We engineered human DIP2C knockout cells by ge...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5513093/ https://www.ncbi.nlm.nih.gov/pubmed/28716088 http://dx.doi.org/10.1186/s12885-017-3472-5 |