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Loss of DIP2C in RKO cells stimulates changes in DNA methylation and epithelial-mesenchymal transition

BACKGROUND: The disco-interacting protein 2 homolog C (DIP2C) gene is an uncharacterized gene found mutated in a subset of breast and lung cancers. To understand the role of DIP2C in tumour development we studied the gene in human cancer cells. METHODS: We engineered human DIP2C knockout cells by ge...

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Detalles Bibliográficos
Autores principales:	Larsson, Chatarina, Ali, Muhammad Akhtar, Pandzic, Tatjana, Lindroth, Anders M., He, Liqun, Sjöblom, Tobias
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5513093/ https://www.ncbi.nlm.nih.gov/pubmed/28716088 http://dx.doi.org/10.1186/s12885-017-3472-5

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