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A rare-variant test for high-dimensional data
Genome-wide association studies have facilitated the discovery of thousands of loci for hundreds of phenotypes. However, the issue of missing heritability remains unsolved for most complex traits. Locus discovery could be enhanced with both improved power through multi-phenotype analysis (MPA) and u...
Autores principales: | Kaakinen, Marika, Mägi, Reedik, Fischer, Krista, Heikkinen, Jani, Järvelin, Marjo-Riitta, Morris, Andrew P, Prokopenko, Inga |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5513099/ https://www.ncbi.nlm.nih.gov/pubmed/28537275 http://dx.doi.org/10.1038/ejhg.2017.90 |
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