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Apixaban for treatment of confirmed heparin-induced thrombocytopenia: a case report and review of literature
BACKGROUND: Heparin-induced thrombocytopenia (HIT) is a life and limb-threatening condition caused by the binding of platelet-activating antibodies (IgG) to multimolecular platelet factor 4 (PF4)/heparin complexes because of heparin exposure. The by-product of this interaction is thrombin formation...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5513338/ https://www.ncbi.nlm.nih.gov/pubmed/28725494 http://dx.doi.org/10.1186/s40164-017-0080-7 |