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Complete response of mediastinal clear cell sarcoma to pembrolizumab with radiotherapy

BACKGROUND: Clear cell sarcoma (CCS) is a rare, aggressive soft tissue sarcoma thought to derive from neural crest and characterized by a 12;22 translocation. The resulting fusion protein directly activates expression of the melanocyte master transcription factor and drives the same down-stream path...

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Detalles Bibliográficos
Autores principales: Marcrom, Samuel, De Los Santos, Jennifer F., Conry, Robert M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5513342/
https://www.ncbi.nlm.nih.gov/pubmed/28725344
http://dx.doi.org/10.1186/s13569-017-0079-1