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The role of microglial P2X7: modulation of cell death and cytokine release

BACKGROUND: ATP-gated P2X7 is a non-selective cation channel, which participates in a wide range of cellular functions as well as pathophysiological processes including neuropathic pain, immune response, and neuroinflammation. Despite its abundant expression in microglia, the role of P2X7 in neuroin...

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Detalles Bibliográficos
Autores principales: He, Yingbo, Taylor, Natalie, Fourgeaud, Lawrence, Bhattacharya, Anindya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5513370/
https://www.ncbi.nlm.nih.gov/pubmed/28716092
http://dx.doi.org/10.1186/s12974-017-0904-8