Active subfractions of Abelmoschus esculentus substantially prevent free fatty acid-induced β cell apoptosis via inhibiting dipeptidyl peptidase-4

Lipotoxicity plays an important role in exacerbating type 2 diabetes mellitus (T2DM) and leads to apoptosis of β cells. Recently dipeptidyl peptidase-4 (DPP-4) inhibitors have emerged as a useful tool in the treatment of T2DM. DPP-4 degrades type 1 glucagon-like peptide (GLP-1), and GLP-1 receptor (...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Chien-Ning, Wang, Chau-Jong, Lee, Yi-Ju, Peng, Chiung-Huei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5513409/
https://www.ncbi.nlm.nih.gov/pubmed/28715446
http://dx.doi.org/10.1371/journal.pone.0180285

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5513409/
https://www.ncbi.nlm.nih.gov/pubmed/28715446
http://dx.doi.org/10.1371/journal.pone.0180285

Ejemplares similares