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A novel isoform of IL-33 revealed by screening for transposable element promoted genes in human colorectal cancer

Remnants of ancient transposable elements (TEs) are abundant in mammalian genomes. These sequences contain multiple regulatory motifs and hence are capable of influencing expression of host genes. TEs are known to be released from epigenetic repression and can become transcriptionally active in canc...

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Detalles Bibliográficos
Autores principales: Lock, Frances E., Babaian, Artem, Zhang, Ying, Gagnier, Liane, Kuah, Sabrina, Weberling, Antonia, Karimi, Mohammad M., Mager, Dixie L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5513427/
https://www.ncbi.nlm.nih.gov/pubmed/28715472
http://dx.doi.org/10.1371/journal.pone.0180659