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A novel isoform of IL-33 revealed by screening for transposable element promoted genes in human colorectal cancer
Remnants of ancient transposable elements (TEs) are abundant in mammalian genomes. These sequences contain multiple regulatory motifs and hence are capable of influencing expression of host genes. TEs are known to be released from epigenetic repression and can become transcriptionally active in canc...
Autores principales: | Lock, Frances E., Babaian, Artem, Zhang, Ying, Gagnier, Liane, Kuah, Sabrina, Weberling, Antonia, Karimi, Mohammad M., Mager, Dixie L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5513427/ https://www.ncbi.nlm.nih.gov/pubmed/28715472 http://dx.doi.org/10.1371/journal.pone.0180659 |
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