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A sequence level model of an intact locus predicts the location and function of nonadditive enhancers
Metazoan gene expression is controlled through the action of long stretches of noncoding DNA that contain enhancers—shorter sequences responsible for controlling a single aspect of a gene’s expression pattern. Models built on thermodynamics have shown how enhancers interpret protein concentration in...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5513433/ https://www.ncbi.nlm.nih.gov/pubmed/28715438 http://dx.doi.org/10.1371/journal.pone.0180861 |