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KSHV encoded ORF59 modulates histone arginine methylation of the viral genome to promote viral reactivation

Kaposi’s sarcoma associated herpesvirus (KSHV) persists in a highly-ordered chromatin structure inside latently infected cells with the majority of the viral genome having repressive marks. However, upon reactivation the viral chromatin landscape changes into ‘open’ chromatin through the involvement...

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Detalles Bibliográficos
Autores principales: Strahan, Roxanne C., McDowell-Sargent, Maria, Uppal, Timsy, Purushothaman, Pravinkumar, Verma, Subhash C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5513536/
https://www.ncbi.nlm.nih.gov/pubmed/28678843
http://dx.doi.org/10.1371/journal.ppat.1006482