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Effects of glucose, insulin, and insulin resistance on cerebral (18)F-FDG distribution in cognitively normal older subjects

BACKGROUND: Increasing plasma glucose levels and insulin resistance can alter the distribution pattern of fluorine-18-labeled fluorodeoxyglucose ((18)F-FDG) in the brain and relatively reduce (18)F-FDG uptake in Alzheimer's disease (AD)-related hypometabolic regions, leading to the appearance o...

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Detalles Bibliográficos
Autores principales: Ishibashi, Kenji, Onishi, Airin, Fujiwara, Yoshinori, Ishiwata, Kiichi, Ishii, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5513548/
https://www.ncbi.nlm.nih.gov/pubmed/28715453
http://dx.doi.org/10.1371/journal.pone.0181400