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Transcriptomes of six mutants in the Sen1 pathway reveal combinatorial control of transcription termination across the Saccharomyces cerevisiae genome

Transcriptome studies on eukaryotic cells have revealed an unexpected abundance and diversity of noncoding RNAs synthesized by RNA polymerase II (Pol II), some of which influence the expression of protein-coding genes. Yet, much less is known about biogenesis of Pol II non-coding RNA than mRNAs. In...

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Detalles Bibliográficos
Autores principales: Chen, Xin, Poorey, Kunal, Carver, Melissa N., Müller, Ulrika, Bekiranov, Stefan, Auble, David T., Brow, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5513554/
https://www.ncbi.nlm.nih.gov/pubmed/28665995
http://dx.doi.org/10.1371/journal.pgen.1006863