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Noroviruses Co-opt the Function of Host Proteins VAPA and VAPB for Replication via a Phenylalanine–Phenylalanine-Acidic-Tract-Motif Mimic in Nonstructural Viral Protein NS1/2

The Norovirus genus contains important human pathogens, but the role of host pathways in norovirus replication is largely unknown. Murine noroviruses provide the opportunity to study norovirus replication in cell culture and in small animals. The human norovirus nonstructural protein NS1/2 interacts...

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Detalles Bibliográficos
Autores principales: McCune, Broc T., Tang, Wei, Lu, Jia, Eaglesham, James B., Thorne, Lucy, Mayer, Anne E., Condiff, Emily, Nice, Timothy J., Goodfellow, Ian, Krezel, Andrzej M., Virgin, Herbert W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5513711/
https://www.ncbi.nlm.nih.gov/pubmed/28698274
http://dx.doi.org/10.1128/mBio.00668-17