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The Protein Interactome of Streptococcus pneumoniae and Bacterial Meta-interactomes Improve Function Predictions

The functions of roughly a third of all proteins in Streptococcus pneumoniae, a significant human-pathogenic bacterium, are unknown. Using a yeast two-hybrid approach, we have determined more than 2,000 novel protein interactions in this organism. We augmented this network with meta-interactome data...

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Detalles Bibliográficos
Autores principales: Wuchty, S., Rajagopala, S. V., Blazie, S. M., Parrish, J. R., Khuri, S., Finley, R. L., Uetz, P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5513735/
https://www.ncbi.nlm.nih.gov/pubmed/28744484
http://dx.doi.org/10.1128/mSystems.00019-17