Apolipoprotein ε7 allele in memory complaints: insights through protein structure prediction

PURPOSE: APOE ε7 gene is a rare mutant form of APOE ε3. The mutation occurs in the lipid-binding domain of APOE. Based on the protein’s structure, APOE ε7 is expected to function in lipid and β-amyloid metabolism, similar to APOE ε4. However, unlike that for APOE ε4, the mechanisms responsible for A...

Descripción completa

Detalles Bibliográficos
Autores principales: Youn, Young Chul, Lim, Yong Kwan, Han, Su-Hyun, Giau, Vo Van, Lee, Mi-Kyung, Park, Kwang-Yeol, Kim, SangYun, Bagyinszky, Eva, An, Seong Soo A, Kim, Hye Ryoun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5513808/
https://www.ncbi.nlm.nih.gov/pubmed/28744113
http://dx.doi.org/10.2147/CIA.S131172

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5513808/
https://www.ncbi.nlm.nih.gov/pubmed/28744113
http://dx.doi.org/10.2147/CIA.S131172

Ejemplares similares