A top-down technique to improve the solubility and bioavailability of aceclofenac: in vitro and in vivo studies

The aim of the present work was to tackle the solubility issue of a biopharmaceutics classification system (BCS)-II drug, aceclofenac. Although a number of attempts to increase the aqueous solubility have been made, none of the methods were taken up for scale-up. Hence size reduction technique by a...

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Detalles Bibliográficos
Autores principales: Narayan, Reema, Pednekar, Abhyuday, Bhuyan, Dipshikha, Gowda, Chaitra, Koteshwara, KB, Nayak, Usha Yogendra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5513828/
https://www.ncbi.nlm.nih.gov/pubmed/28744125
http://dx.doi.org/10.2147/IJN.S141504

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5513828/
https://www.ncbi.nlm.nih.gov/pubmed/28744125
http://dx.doi.org/10.2147/IJN.S141504

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