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Spotlight on ramucirumab in the treatment of nonsmall cell lung cancer: design, development, and clinical activity

The vascular endothelial growth factor (VEGF) and receptor is a therapeutic target because of the importance of this pathway in carcinogenesis. This pathway regulates and promotes angiogenesis as well as increases endothelial cell proliferation, permeability, and cancer survival. Ramucirumab is a ne...

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Detalles Bibliográficos
Autores principales: Cobo, Manuel, Gutiérrez, Vanesa, Villatoro, Rosa, Trigo, Jose Manuel, Ramos, Inmaculada, López, Omar, Ruiz, María, Godoy, Ana, López, Irene, Arroyo, Macarena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5513829/
https://www.ncbi.nlm.nih.gov/pubmed/28744168
http://dx.doi.org/10.2147/LCTT.S118996