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Spotlight on ramucirumab in the treatment of nonsmall cell lung cancer: design, development, and clinical activity
The vascular endothelial growth factor (VEGF) and receptor is a therapeutic target because of the importance of this pathway in carcinogenesis. This pathway regulates and promotes angiogenesis as well as increases endothelial cell proliferation, permeability, and cancer survival. Ramucirumab is a ne...
Autores principales: | Cobo, Manuel, Gutiérrez, Vanesa, Villatoro, Rosa, Trigo, Jose Manuel, Ramos, Inmaculada, López, Omar, Ruiz, María, Godoy, Ana, López, Irene, Arroyo, Macarena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5513829/ https://www.ncbi.nlm.nih.gov/pubmed/28744168 http://dx.doi.org/10.2147/LCTT.S118996 |
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