Selective κ receptor partial agonist HS666 produces potent antinociception without inducing aversion after i.c.v. administration in mice

BACKGROUND AND PURPOSE: The κ receptor has a central role in modulating neurotransmission in central and peripheral neuronal circuits that subserve pain and other behavioural responses. Although κ receptor agonists do not produce euphoria or lead to respiratory suppression, they induce dysphoria and...

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Detalles Bibliográficos
Autores principales: Spetea, Mariana, Eans, Shainnel O, Ganno, Michelle L, Lantero, Aquilino, Mairegger, Michael, Toll, Lawrence, Schmidhammer, Helmut, McLaughlin, Jay P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5513865/
https://www.ncbi.nlm.nih.gov/pubmed/28494108
http://dx.doi.org/10.1111/bph.13854

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5513865/
https://www.ncbi.nlm.nih.gov/pubmed/28494108
http://dx.doi.org/10.1111/bph.13854

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