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ALK and ROS1 concurrent with EGFR mutation in patients with lung adenocarcinoma

PURPOSE: The purpose of this study was to explore the frequencies of ALK and ROS1 fusion genes in EGFR-mutant lung adenocarcinoma patients and examine the therapeutic efficacies of EGFR-tyrosine kinase inhibitors (TKIs). MATERIALS AND METHODS: A total of 421 EGFR-mutated patients taking EGFR-TKIs we...

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Detalles Bibliográficos
Autores principales: Mao, Yanjiao, Wu, Shixiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5513887/
https://www.ncbi.nlm.nih.gov/pubmed/28744144
http://dx.doi.org/10.2147/OTT.S133349