Lovastatin Alleviates Endothelial-to-Mesenchymal Transition in Glomeruli via Suppression of Oxidative Stress and TGF-β1 Signaling

Statins may decrease chronic kidney diseases (CKDs) risk, but their underlying molecular mechanisms are not completely understood. Recent studies indicate Endothelial-to-mesenchymal transition (EndMT) plays an important role contributing to renal interstitial fibrosis. In the present study, we first...

Descripción completa

Detalles Bibliográficos
Autores principales: Ma, Zejun, Zhu, Lili, Liu, Yan, Wang, Zhida, Yang, Yang, Chen, Liming, Lu, Qiulun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5513942/
https://www.ncbi.nlm.nih.gov/pubmed/28769803
http://dx.doi.org/10.3389/fphar.2017.00473

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5513942/
https://www.ncbi.nlm.nih.gov/pubmed/28769803
http://dx.doi.org/10.3389/fphar.2017.00473

Ejemplares similares