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Development of a sandwich enzyme-linked immunosorbent assay for dTMP-GH fusion protein by rational immunogen selection

dTMP-GH is a chimeric protein containing a tandem dimer of thrombopoietin mimetic peptide (dTMP) fused to human growth hormone (hGH) prepared previously by our team. It shows significant bioactivity in promoting thrombocytopoiesis, but detection of intact dTMP-GH in plasma is still a challenge due t...

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Detalles Bibliográficos
Autores principales: Wang, Song, Shen, Mingqiang, Chen, Shilei, Wang, Cheng, Chen, Fang, Chen, Mo, Zhao, Gaomei, Ran, Xinze, Cheng, Tianmin, Su, Yongping, Xu, Yang, Wang, Junping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514005/
https://www.ncbi.nlm.nih.gov/pubmed/28724261
http://dx.doi.org/10.1186/s13568-017-0454-6