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FGF18 signaling in the hair cycle resting phase determines radioresistance of hair follicles by arresting hair cycling

PURPOSE: Telogen (resting phase) hair follicles (HFs) are more radioresistant than their anagen (growth phase) counterparts. Fibroblast growth factor (FGF) 18 is strongly expressed in telogen HFs to maintain the telogen phase, whereas several other FGFs exert radioprotective effects; however, the ro...

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Detalles Bibliográficos
Autores principales: Kawano, Mitsuko, Umeda, Sachiko, Yasuda, Takeshi, Fujita, Mayumi, Ishikawa, Atsuko, Imamura, Toru, Imai, Takashi, Nakayama, Fumiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514016/
https://www.ncbi.nlm.nih.gov/pubmed/28740887
http://dx.doi.org/10.1016/j.adro.2016.05.004