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Snake venom VEGF Vammin induces a highly efficient angiogenic response in skeletal muscle via VEGFR-2/NRP specific signaling

Vascular Endothelial Growth Factors (VEGFs) are promising molecules for the treatment of ischemic diseases by pro-angiogenic therapy. Snake venom VEGFs are a novel subgroup with unique receptor binding profiles and as such are potential new therapeutic agents. We determined the ligand-receptor inter...

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Detalles Bibliográficos
Autores principales: Toivanen, Pyry I., Nieminen, Tiina, Laakkonen, Johanna P., Heikura, Tommi, Kaikkonen, Minna U., Ylä-Herttuala, Seppo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514023/
https://www.ncbi.nlm.nih.gov/pubmed/28717175
http://dx.doi.org/10.1038/s41598-017-05876-y