CDK5-mediated phosphorylation of XBP1s contributes to its nuclear translocation and activation in MPP(+)-induced Parkinson’s disease model

Parkinson’s disease (PD) is an irreversible and progressive neurodegenerative disorder characterized by the selective loss of dopaminergic neurons of the substantia nigra pars compacta. Growing evidence indicates that endoplasmic reticulum stress is a hallmark of PD; however, its exact contribution...

Descripción completa

Detalles Bibliográficos
Autores principales: Jiao, Feng-Juan, Wang, Qing-Zhi, Zhang, Pei, Yan, Jian-Guo, Zhang, Zheng, He, Feng, Zhang, Qian, Lv, Ze-Xi, Peng, Xiang, Cai, Hong-Wei, Tian, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514026/
https://www.ncbi.nlm.nih.gov/pubmed/28717189
http://dx.doi.org/10.1038/s41598-017-06012-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514026/
https://www.ncbi.nlm.nih.gov/pubmed/28717189
http://dx.doi.org/10.1038/s41598-017-06012-6

Ejemplares similares