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CDK5-mediated phosphorylation of XBP1s contributes to its nuclear translocation and activation in MPP(+)-induced Parkinson’s disease model
Parkinson’s disease (PD) is an irreversible and progressive neurodegenerative disorder characterized by the selective loss of dopaminergic neurons of the substantia nigra pars compacta. Growing evidence indicates that endoplasmic reticulum stress is a hallmark of PD; however, its exact contribution...
Autores principales: | Jiao, Feng-Juan, Wang, Qing-Zhi, Zhang, Pei, Yan, Jian-Guo, Zhang, Zheng, He, Feng, Zhang, Qian, Lv, Ze-Xi, Peng, Xiang, Cai, Hong-Wei, Tian, Bo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514026/ https://www.ncbi.nlm.nih.gov/pubmed/28717189 http://dx.doi.org/10.1038/s41598-017-06012-6 |
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