Epithelial cell specific Raptor is required for initiation of type 2 mucosal immunity in small intestine

Intestinal tuft cells are one of 4 secretory cell linages in the small intestine and the source of IL-25, a critical initiator of the type 2 immune response to parasite infection. When Raptor, a critical scaffold protein for mammalian target of rapamycin complex 1 (mTORC1), was acutely deleted in in...

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Detalles Bibliográficos
Autores principales: Aladegbami, Bola, Barron, Lauren, Bao, James, Colasanti, Jason, Erwin, Christopher R., Warner, Brad W., Guo, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514129/
https://www.ncbi.nlm.nih.gov/pubmed/28717211
http://dx.doi.org/10.1038/s41598-017-06070-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514129/
https://www.ncbi.nlm.nih.gov/pubmed/28717211
http://dx.doi.org/10.1038/s41598-017-06070-w

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