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Epithelial cell specific Raptor is required for initiation of type 2 mucosal immunity in small intestine
Intestinal tuft cells are one of 4 secretory cell linages in the small intestine and the source of IL-25, a critical initiator of the type 2 immune response to parasite infection. When Raptor, a critical scaffold protein for mammalian target of rapamycin complex 1 (mTORC1), was acutely deleted in in...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514129/ https://www.ncbi.nlm.nih.gov/pubmed/28717211 http://dx.doi.org/10.1038/s41598-017-06070-w |