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Discovery of Novel Human Gene Regulatory Modules from Gene Co-expression and Promoter Motif Analysis

Deciphering gene regulatory networks requires identification of gene expression modules. We describe a novel bottom-up approach to identify gene modules regulated by cis-regulatory motifs from a human gene co-expression network. Target genes of a cis-regulatory motif were identified from the network...

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Detalles Bibliográficos
Autores principales: Ma, Shisong, Snyder, Michael, Dinesh-Kumar, Savithramma P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514134/
https://www.ncbi.nlm.nih.gov/pubmed/28717181
http://dx.doi.org/10.1038/s41598-017-05705-2