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A mammalian mirtron miR-1224 promotes tube-formation of human primary endothelial cells by targeting anti-angiogenic factor epsin2

Angiogenesis, new vessel formation from pre-existing vessels, is a highly conserved event through vertebrates. However, the system for tuning angiogenesis by species-intrinsic factors is totally unknown. miR-1224 is a member of mammal-specific mirtrons, which were identified as non-canonical microRN...

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Detalles Bibliográficos
Autores principales: Sakai, Eiko, Miura, Yusuke, Suzuki-Kouyama, Emi, Oka, Kengo, Tachibana, Masashi, Kawabata, Kenji, Sakurai, Fuminori, Mizuguchi, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514154/
https://www.ncbi.nlm.nih.gov/pubmed/28717225
http://dx.doi.org/10.1038/s41598-017-05782-3