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Mitochondria in Cell Senescence: Is Mitophagy the Weakest Link?

Cell senescence is increasingly recognized as a major contributor to the loss of health and fitness associated with aging. Senescent cells accumulate dysfunctional mitochondria; oxidative phosphorylation efficiency is decreased and reactive oxygen species production is increased. In this review we w...

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Detalles Bibliográficos
Autores principales: Korolchuk, Viktor I., Miwa, Satomi, Carroll, Bernadette, von Zglinicki, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514379/
https://www.ncbi.nlm.nih.gov/pubmed/28330601
http://dx.doi.org/10.1016/j.ebiom.2017.03.020