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Mitochondria in Cell Senescence: Is Mitophagy the Weakest Link?
Cell senescence is increasingly recognized as a major contributor to the loss of health and fitness associated with aging. Senescent cells accumulate dysfunctional mitochondria; oxidative phosphorylation efficiency is decreased and reactive oxygen species production is increased. In this review we w...
Autores principales: | Korolchuk, Viktor I., Miwa, Satomi, Carroll, Bernadette, von Zglinicki, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514379/ https://www.ncbi.nlm.nih.gov/pubmed/28330601 http://dx.doi.org/10.1016/j.ebiom.2017.03.020 |
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