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Combined Mass Spectrometry Imaging and Top-down Microproteomics Reveals Evidence of a Hidden Proteome in Ovarian Cancer

BACKGROUND: Recently, it was demonstrated that proteins can be translated from alternative open reading frames (altORFs), increasing the size of the actual proteome. Top-down mass spectrometry-based proteomics allows the identification of intact proteins containing post-translational modifications (...

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Detalles Bibliográficos
Autores principales: Delcourt, Vivian, Franck, Julien, Leblanc, Eric, Narducci, Fabrice, Robin, Yves-Marie, Gimeno, Jean-Pascal, Quanico, Jusal, Wisztorski, Maxence, Kobeissy, Firas, Jacques, Jean-François, Roucou, Xavier, Salzet, Michel, Fournier, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514399/
https://www.ncbi.nlm.nih.gov/pubmed/28629911
http://dx.doi.org/10.1016/j.ebiom.2017.06.001