Histone Chaperone ASF1A Predicts Poor Outcomes for Patients With Gastrointestinal Cancer and Drives Cancer Progression by Stimulating Transcription of β-Catenin Target Genes

Epigenetic mechanisms play a key role in gastrointestinal cancer (GIC) development and progression, and most studies have been focused on aberrant DNA methylation and histone modifying enzymes. However, the histone H3–H4 chaperone ASF1A is an important factor regulating chromatin assembling and gene...

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Detalles Bibliográficos
Autores principales: Liang, Xiuming, Yuan, Xiaotian, Yu, Jingya, Wu, Yujiao, Li, Kailin, Sun, Chao, Li, Shuyan, Shen, Li, Kong, Feng, Jia, Jihui, Björkholm, Magnus, Xu, Dawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514402/
https://www.ncbi.nlm.nih.gov/pubmed/28625518
http://dx.doi.org/10.1016/j.ebiom.2017.06.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514402/
https://www.ncbi.nlm.nih.gov/pubmed/28625518
http://dx.doi.org/10.1016/j.ebiom.2017.06.007

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