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Quantitation of DNA methylation in Epstein-Barr virus–associated nasopharyngeal carcinoma by bisulfite amplicon sequencing

BACKGROUND: Epigenetic changes, including DNA methylation, disrupt normal cell function, thus contributing to multiple steps of carcinogenesis. Nasopharyngeal carcinoma (NPC) is endemic in southern China and is highly associated with Epstein-Barr virus (EBV) infection. Significant changes of the hos...

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Detalles Bibliográficos
Autores principales: Zhao, Weilin, Mo, Yingxi, Wang, Shumin, Midorikawa, Kaoru, Ma, Ning, Hiraku, Yusuke, Oikawa, Shinji, Huang, Guangwu, Zhang, Zhe, Murata, Mariko, Takeuchi, Kazuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514474/
https://www.ncbi.nlm.nih.gov/pubmed/28716111
http://dx.doi.org/10.1186/s12885-017-3482-3