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Colony-stimulating factor 1 receptor (CSF1R) inhibitors in cancer therapy

The tumor-permissive and immunosuppressive characteristics of tumor-associated macrophages (TAM) have fueled interest in therapeutically targeting these cells. In this context, the colony-stimulating factor 1 (CSF1)/colony-stimulating factor 1 receptor (CSF1R) axis has gained the most attention, and...

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Detalles Bibliográficos
Autores principales: Cannarile, Michael A., Weisser, Martin, Jacob, Wolfgang, Jegg, Anna-Maria, Ries, Carola H., Rüttinger, Dominik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514481/
https://www.ncbi.nlm.nih.gov/pubmed/28716061
http://dx.doi.org/10.1186/s40425-017-0257-y