Cargando…

Probucol ameliorates renal injury in diabetic nephropathy by inhibiting the expression of the redox enzyme p66Shc

AIMS: Probucol is an anti-hyperlipidemic agent and a potent antioxidant drug that can delay progression of diabetic nephropathy (DN) and reverses renal oxidative stress in diabetic animal models; however, the mechanisms underlying these effects remain unclear. p66Shc is a newly recognized mediator o...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Shikun, Zhao, Li, Han, Yachun, Liu, Yu, Chen, Chao, Zhan, Ming, Xiong, Xiaofen, Zhu, Xuejing, Xiao, Li, Hu, Chun, Liu, Fuyou, Zhou, Zhiguang, Kanwar, Yashpal S., Sun, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514499/
https://www.ncbi.nlm.nih.gov/pubmed/28728079
http://dx.doi.org/10.1016/j.redox.2017.07.002