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Probucol ameliorates renal injury in diabetic nephropathy by inhibiting the expression of the redox enzyme p66Shc
AIMS: Probucol is an anti-hyperlipidemic agent and a potent antioxidant drug that can delay progression of diabetic nephropathy (DN) and reverses renal oxidative stress in diabetic animal models; however, the mechanisms underlying these effects remain unclear. p66Shc is a newly recognized mediator o...
Autores principales: | Yang, Shikun, Zhao, Li, Han, Yachun, Liu, Yu, Chen, Chao, Zhan, Ming, Xiong, Xiaofen, Zhu, Xuejing, Xiao, Li, Hu, Chun, Liu, Fuyou, Zhou, Zhiguang, Kanwar, Yashpal S., Sun, Lin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514499/ https://www.ncbi.nlm.nih.gov/pubmed/28728079 http://dx.doi.org/10.1016/j.redox.2017.07.002 |
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