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FOXP3 promotes tumor growth and metastasis by activating Wnt/β-catenin signaling pathway and EMT in non-small cell lung cancer

BACKGROUND: The role of cancer cell FOXP3 in tumorigenesis is conflicting. We aimed to study FOXP3 expression and regulation, function and clinical implication in human non-small cell lung cancer (NSCLC). METHODS: One hundred and six patients with histologically-confirmed NSCLC who underwent surgery...

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Detalles Bibliográficos
Autores principales: Yang, Shucai, Liu, Yi, Li, Ming-Yue, Ng, Calvin S. H., Yang, Sheng-li, Wang, Shanshan, Zou, Chang, Dong, Yujuan, Du, Jing, Long, Xiang, Liu, Li-Zhong, Wan, Innes Y. P., Mok, Tony, Underwood, Malcolm J., Chen, George G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514503/
https://www.ncbi.nlm.nih.gov/pubmed/28716029
http://dx.doi.org/10.1186/s12943-017-0700-1