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MiR-661 promotes tumor invasion and metastasis by directly inhibiting RB1 in non small cell lung cancer

BACKGROUND: Aberrant microRNA expression has been implicated in metastasis of cancers. MiR-661 accelerates proliferation and invasion of breast cancer and ovarian cancer, while impedes that of glioma. Its role in non small cell lung cancer (NSCLC) and underlying mechanism are worthy elucidation. MET...

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Detalles Bibliográficos
Autores principales: Liu, Feiye, Cai, Yanjun, Rong, Xiaoxiang, Chen, Jinzhang, Zheng, Dayong, Chen, Lu, Zhang, Junyi, Luo, Rongcheng, Zhao, Peng, Ruan, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514511/
https://www.ncbi.nlm.nih.gov/pubmed/28716024
http://dx.doi.org/10.1186/s12943-017-0698-4