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Detecting protein variants by mass spectrometry: a comprehensive study in cancer cell-lines
BACKGROUND: Onco-proteogenomics aims to understand how changes in a cancer’s genome influences its proteome. One challenge in integrating these molecular data is the identification of aberrant protein products from mass-spectrometry (MS) datasets, as traditional proteomic analyses only identify prot...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514513/ https://www.ncbi.nlm.nih.gov/pubmed/28716134 http://dx.doi.org/10.1186/s13073-017-0454-9 |