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Detecting protein variants by mass spectrometry: a comprehensive study in cancer cell-lines

BACKGROUND: Onco-proteogenomics aims to understand how changes in a cancer’s genome influences its proteome. One challenge in integrating these molecular data is the identification of aberrant protein products from mass-spectrometry (MS) datasets, as traditional proteomic analyses only identify prot...

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Detalles Bibliográficos
Autores principales: Alfaro, Javier A., Ignatchenko, Alexandr, Ignatchenko, Vladimir, Sinha, Ankit, Boutros, Paul C., Kislinger, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514513/
https://www.ncbi.nlm.nih.gov/pubmed/28716134
http://dx.doi.org/10.1186/s13073-017-0454-9