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The role of tumour heterogeneity and clonal cooperativity in metastasis, immune evasion and clinical outcome

BACKGROUND: The advent of rapid and inexpensive sequencing technology allows scientists to decipher heterogeneity within primary tumours, between primary and metastatic sites, and between metastases. Charting the evolutionary history of individual tumours has revealed drivers of tumour heterogeneity...

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Detalles Bibliográficos
Autores principales: Caswell, Deborah R., Swanton, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514532/
https://www.ncbi.nlm.nih.gov/pubmed/28716075
http://dx.doi.org/10.1186/s12916-017-0900-y