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Can a fibrotic liver afford epithelial-mesenchymal transition?

The question whether epithelial-mesenchymal transition (EMT) occurs during liver fibrogenesis is a controversial issue. In vitro studies confirm that hepatocytes or cholangiocytes undergo EMT upon transforming growth factor β (TGF-β) stimulation, whereas in vivo experiments based on genetic fate map...

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Detalles Bibliográficos
Autores principales: Munker, Stefan, Wu, Yong-Le, Ding, Hui-Guo, Liebe, Roman, Weng, Hong-Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514631/
https://www.ncbi.nlm.nih.gov/pubmed/28765687
http://dx.doi.org/10.3748/wjg.v23.i26.4661