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Fibrinogen deficiency suppresses the development of early and delayed radiation enteropathy

AIM: To determine the mechanistic role of fibrinogen, a key regulator of inflammation and fibrosis, in early and delayed radiation enteropathy. METHODS: Fibrinogen wild-type (Fib(+/+)), fibrinogen heterozygous (Fib(+/-)), and fibrinogen knockout (Fib(-/-)) mice were exposed to localized intestinal i...

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Detalles Bibliográficos
Autores principales: Wang, Junru, Pathak, Rupak, Garg, Sarita, Hauer-Jensen, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514635/
https://www.ncbi.nlm.nih.gov/pubmed/28765691
http://dx.doi.org/10.3748/wjg.v23.i26.4701